I upgraded to 16.10 a few days ago and had a total freeze on the system; unresponsive cursor, couldn't exit X and had to force shutdown vi the power button. After that I have been experiencing problems with a dual display setup which don't allow arranging them. Instead the system logs out.
Furthermore the touchpad settings are not visible any longer and I cannot change the scrolling method to natural scrolling. The dconf editor (under org> gnome> desktop> peripherals> touchpad) states that the natural-scroll setting is enabled though. The scenario is similar to this. I've got
xserver-xorg-input-synaptics installed instead of
Ubuntu Gnome 16.10 running on a 13" MacBook 5,1 (2009)