You'll have one beast of an Ubuntu machine!
The only potential conflict would be the graphics card, but drivers for that can be easily installed if you feel like you need them.
Otherwise, I foresee no problems installing Ubuntu, though if you're installing to an SSD, I'd recommend not adding a swap partition, as you have more than enough RAM. If you do run into errors where you run out of RAM, it may be a good idea to buy a classic hard drive for swap and
/tmp and any other frequently-altered data, but this is not explicitly necessary.
If I were in your shoes, I would have most everything off the SSD, so that it can be saved for important things. For example, I'd store videos and the like on the hard drive, and just symlink my ~/Videos over to my HDD. Similarly, I'd probably have
/tmp and the like stored on my HDD, but such a setup may very well give you little to no benefit, but it is something to keep in mind.