My motherboard is Supermicro X10SRA-F Version 1.01. Can I safely upgrade from Ubuntu 14.04 LTS to Ubuntu 16.04 LTS with respect to compatibility? Thanks
Upgrading distributions to a newer version rarely causes hardware support issues because in the kernel, support for hardware is rarely (if not never) removed, only added.
If you really want to be sure, try it with a live usb with 16.04 without installing it, that usually is a good indicator of what to expect when you actually install it. And if that works, you can be quite sure that it will work.