In 16.04 LTS support for AMD proprietary drivers has been dropped. Instead there's an open source AMDGPU driver. My Question: Will the ATI Radeon HD 5450 work with the open source AMDGPU driver?
closed as primarily opinion-based by mikewhatever, Pilot6, muru, Eric Carvalho, user117103 Apr 6 '16 at 18:19
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According to the official release notes of Ubuntu 16.04 (Xenial Xerus), the open source ADMGPU driver should support most AMD graphics cards, so I can safely say yes, your graphics card should be supported.
However, I do recommend that when the official release of Ubuntu 16.04 comes (April 21), be sure to install using a live disc or a bootable disk to try out Ubuntu 16.04 and see how it performs on that particular machine, before doing a full installation.