I am using ubuntu 14.04LTS.

I ran

$sudo dpkg -i virtualbox-5.0_5.0.4-102546-Ubuntu-trusty_amd64.deb 


Failed to create VirtualBoxClient COM Object.The application will now terminate.

Callee RC: 

We resolved this in chat here.

Quick explanation of how we resolved it:

OP had downloaded the .deb file from here.

  1. Run sudo apt-get purge virtualbox
  2. Reboot the machine
  3. Run sudo dpkg -i virtualbox-5.0_5.0.4-102546-Ubuntu-trusty_amd64.deb.
  4. Run virtualbox and it now works!

Apparently a reboot was required.

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