The monitor can go into a flickering mode which is easily triggered by going into "Search your computer and online sources." It is especially bad if other applications are open like Chrome (perhaps opengl related). It can go into a loop that will get so bad that a reboot is necessary. It is not reliable.
I have tried disabling (in compiz-settings-manager) "Unredirect Fullscreen Windows." Also tried increasing the "Launcher reveal Pressure."
So far, since I have only seen this triggered by using the "Search your computer and online sources," I'm wondering if there is a second interface (perhaps text only) that users can use until there is fix..
In the mean time, I have made it stable by decreased the display resolution from
3840 x 2160 to
1920 x 1080.
lspci | grep VGA 00:02.0 VGA compatible controller: Intel Corporation Broadwell-U Integrated Graphics (rev 09) 08:00.0 VGA compatible controller: Advanced Micro Devices, Inc. [AMD/ATI] Opal XT [Radeon R7 M265] (rev ff)