I'm running Precise Pangolin with GNOME 3.4. Whenever I run a WINE Application there is a chance that the application will show a black screen and a chance that it might run properly. I haven't found a way to exit the black screen besides rebooting the entire system. Ubuntu seems to be still running properly in the background but I can't access the terminal or anything else. If rhythmbox is open the music keeps playing. I didn't have this problem with the same WINE applications on OpenSUSE 12 or Oneiric Ocelot but back then I was running GNOME 3.2. The applications run smoothly on Windows 7. It's really annoying to reboot the system every time WINE displays a black screen so is I'm wondering, is there a workaround for this?
That happens to me too sometimes.
In my case I just close or exit the wine application by pressing
Alt+F4. If that doesn't close wine, try pressing
CTRL+ALT+F1 to switch to console mode and kill wine from there.