Wine applications load very slowly on my Kubuntu. It is common knowledge that one should autostart the Wine server to run persistently:
wineserver -p
This significantly reduces the per-program loading time, but it is not enough: on my reasonably modern computer it takes about a second to start a simple wine application after the first time, way more than it should.
Searching for solutions online yielded mainly the answer of oiaohm in this WineHQ Forum question (see also the associated duplicate bug reports here and here). The first issue oiaohm raises is that there are "too many" fonts installed, and that wine producing a very long font list leads to long startup times. It turned out that the font issue really was the reason for Wine's slow startup in my computer. Kubuntu has many fonts installed by default, see, e.g., the wide Noto fonts family. Removing fonts only because of their effect on Wine makes no sense. And even if one wanted to remove some of the fonts, doing so by removing their packages is not always possible due to dependencies. In his/her answer, oiaohm suggested to use a custom fontconfig file, but didn't elaborate.
I am thus looking for some, preferably "natural", solution to this problem. Below, as an answer, is the solution I found. Suggestions for better ones are warmly welcome.