The new versions are significantly more beginner friendly than in the past. Jack2, Pulseaudio and ALSA are preconfigured to work together and the audio configuration application (called Ubuntu studio controls) has an audio setup dialog where everything is easy to reconfigure and restart.
In the past and in other distributions I used custom shell scripts for such things, here it just works. Carla is included and set up so that you can visually connect hardware devices, inputs, outputs and virtual plugins.
There is a nice handbook that can get you started, you can look into it and see how things are setup. - https://ubuntustudio.org/audio-handbook/ (the link is visible from the official web-site homepage)
The only thing you need to check is if the specific hardware you have or that you want to use in the future, works at all under linux. For this I would recommend checking the forums on https://linuxmusicians.com/ (where there is already a recent discussion on Scarlett 18i20) and also the http://opensourcemusician.com/index.php?title=Main_Page (and the freenode IRC channel #opensourcemusicians linked from the website).
In the end, you can always check if you like and if things work before installing, by running it live from a boot-able USB stick (or DVD if you prefer). Just download the latest official version from https://ubuntustudio.org/ and use the standard procedure to create a boot-able stick describet at https://ubuntu.com/tutorials/tutorial-create-a-usb-stick-on-windows. Currently the pre-release version 20.04 due to be released in April is under wider testing, check https://ubuntustudio.org/2020/03/ubuntu-studio-20-04-testing-week/ on how to get it.