I have much trouble with Ubuntu 11.10. I have a quite new system with an ASUS M5A97, and neither NIC nor USB 2.0 are working. The first problem could be solved by using a vendor driver, but the latter still exists. Mouse (Logitech MX900) and keyboard (Logitech Illuminated KB) are not recognized. I have older devices with I have kept for emergencies plugged to USB 3.0 or PS/2 which are then regognized and working.
This chipset problem almost only exists in Ubuntu, live CDs based on other distrubutions (System Rescue CD, Parted Magic) work just fine. There is a guy reporting to have the same problem with Archlinux, but it hasn't been solved to date:
Is there any chance that this issue (the board is out for sale since january) will be solved one day? Has anyone an idea what to do to get the onboard USB running? Apart from switching to another distribution, of course.