I have 2x mice, 2x keybard, 2x monitor 1x graphics.
Can I make it a second computer? (for no reason at all)
--OR--
Would it be easier with a second VGA: As I do have a decent extra ATI card (7750 series) HOWEVER... I am currently using Nvidia
You could always get a KVM switch. This will let you switch back and forth between mice, keyboard, monitors, with the press of a button, but you would need 2 computers connected to the switch.
Check this one out for multiseated device, which is what I believe you are trying to do.