According to the Wine Wiki,
wineprefixcreate is now deprecated and there is no need to run it anymore.
Just run wine and everything happens automatically. It was for [a]
manual update of a WINE prefix. Now it is automatic and therefore it
isn't needed anymore.
Also take a look at the screenshot in the article linked in the Question:
It also displays a Notice:
wineprefixcreate is deprecated and shouldn't be needed anymore.
WINEPREFIX creation and updates now happen automatically when needed.
Thus all you should do is to set the
WINEPREFIX variable and run your game with wine.
You should run something similar:
WINEPREFIX="/home/zach/Neverwinter" wine /path/to/your-neverwinter-setup.exe
Just to make sure I've just run a test case:
WINEPREFIX="/home/user/WINETEST" wine regedit.exe
A window opened stating the wine environment is getting refreshed and then the registry editor started up.
As soulsource has pointed out, the prefix directory should not be created beforehand. It can cause issues when it already exists. Just run wine with the appropriate prefix set and it will be created properly. As the comment states:
Small sidenote: If you want to create a new WINEPREFIX, do not create
the directory beforehand. Wine will create it on the first run with
the appropriate WINEPREFIX automatically. If the directory already
exists, numerous issues can arise, the most prominent is that the
WINEARCH setting is ignored. "Note: During prefix creation, the 64-bit
version of wine treats all folders as 64-bit prefixes and will not
create a 32-bit in any existing folder. To create a 32-bit prefix you
have to let wine create the folder specified in WINEPREFIX."
Source: ArchWiki - Using WINEARCH