As long as the two anti-virus programs do not collide with each other, it probably is not a problem, but you would have to know something about how each anti-virus works.
Depending on how robust your system is, running one anti-virus program logically consumes some system resources, so running two anti-virus programs will consume more. You will have to decide if that is worth it.
I have asked a lot of questions over the years about the need to run Linux/Unix a anti-virus program, and basically have been told that unless I was hosting a shared drive for Windows users, running Linux anti-virus was overkill, and, at one time, I had purchased NOD32, which is quite good and well know on Windows and Linux.
Of course, things change, and hopefully someone else will weigh in on this question.