I have two applications that run through Wine that will sometimes get horribly distorted and "sped forward" (I can see in Spotify that the files are played back much faster than they should be). I tested it today and was able to play music in Spotify for a while, perhaps 15 minutes. I also tried to test audio in Wine and that seemed fine, too. I started the other application and the sound was fine there too, for the most part: it was a little choppy sometimes which seemed to correlate with how rapidly I changed between audio tracks. In Spotify, though the sound was mostly fine, there was some small hiccups with the playback sometimes, but I don't know if that is a symptom of the overarching problem with Wine.
After a while Spotify began to ouput audio that was distorted and sped-forward. It was pretty consistent; sometimes it would return to normal, but for the most part it was just useless. The other application and wine-config audio testoutputted horrible audio, too.
Driver used: winealsa.drv.