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This question already has an answer here:

Is it possible to run Ubuntu from the USB-drive only, without getting all changes wiped at restart?

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marked as duplicate by Eric Carvalho, hhlp, Eliah Kagan, Mik, gertvdijk Feb 9 '13 at 23:47

This question has been asked before and already has an answer. If those answers do not fully address your question, please ask a new question.

Yes, it's possible. The changes are saved on a persistence file which needs to be created when making the diskimage. If you're making the flash-drive image from windows, I presume you're using Universal-USB-Installer, set the persistent file size according to your requirements.universal-usb-installer

Or if you're doing this from some linux distro, you're probably using Unetbootin. In that case, change the persistent space value as per your needs. unetbootin

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Thanks, that really helped :) – UbuntuKat Feb 9 '13 at 9:48

I believe you will find your answer here in great detail: How do I install Ubuntu to a USB key? Just scroll down to the best answer choose by the user explaining how to use "testdrive".

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