I am trying configure the Calculator to do some binary to hexadecimal conversions but I can't seem to get to scientific mode. Please can someone tell me how I configure?
The Calculator has various modes. What you are looking for is the Programming mode, which lets you display numbers in various bases. To use it, select Calculator › Programming from the menu.
As you asked for the scientific mode, I must add that functions commonly used in scientific calculations are available using Calculator › Advanced.