I have my / and /Home on a 120GB SSD and data and SWAP are on a mechanical Hard Drive. Will using Hibernation have a negative impact on my SSD or is it OK as SWAP is not on that drive?
In theory, it would since Hibernation writes everything to ssd, it would increase writes to your ssd > reduce its life.
In real life, most modern ssd can last very long so Hibernation isnt a big problem.
if you want to tweak and optimize SSD for Ubuntu, disable Hibernation
Change from “yes” to “no”, there are two, one for hibernation, and another one for suspend. If you have to disable them both, make sure to replace them both from yes to no.