Using 12.04, 64bit. Does not happen in Firefox though.
After some time, the flash videos in the Chrome browser start to speed up. Resulting in crackled sound and generally making the videos unwatchable. Further, I can hear some random crackles - even with no sound playing application open. Cant clear say what causes this. I had times where I could watch several videos for 2 hours straight, next day the problems began after less than 20 minutes.
Needs reboot to resolve my problem.
Other audio applications like Banshee or HTML5 videos are not effected, event not in Chrome.