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Guitar Pro has native Linux version. Similar open-source app is Tuxguitar. You can install it from the Software Center.

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Dear Lord, how long has the native version been out?! :) I've never even heard of that! – Ryan McClure Mar 25 '12 at 5:41

Wine and PlayOnLinux (Both available on the Software Center) will allow the program to run.

(I have tried GP5 but not 6...I know for a fact 5 works)

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