I am no expert on Wine, but the following solution has helped a number of people with sound problems on wine (it does work for 64bit too).
Marvin Mallari posted to Ubuntu 15 hours ago - For people having sound problems with Wine (like sound is garbled, static, non existant) in Ubuntu 12.04 (w/ Unity and Pulse/ALSA) i found a solution. Go to Synaptic Package Manager, install "ia32-libs-multiarch", it will ask to modify or install other packages, install all packages and restart (not log out then log in) Wine should now play audio perfectly and stable. note: i did this on a 32bit comp, for 64bit, there is probably a different package or maybe the package will work because it says "multiarch" i will try on my 64bit machine later. PS i don't have an account on any Wine or Ubuntu fourms so if someone can please share this somewhere that needs it that would be much appreciated!
Marvin Mallari - Ia32 probably isn't the solution but when I read the
addition packages synaptic modifies and installs, a couple of them are
for pulse so it is probably those packages that fixed it but in any
case ia32 installed whatever it needed to work. It also seems like
pulse cpu usage has dropped.
d3dx90_36
with winetricks? Check out Civilization 5 on WineHQ.